Citrulline amino acid is converted to arginine by specific enzymes. Arginine is an amino acid that works wonders for the heart and circulatory system, and it keeps the immune system functioning well. The relationship between citrulline and arginine supports healthy heart and immune system development. At the same time, the relationship is good for people with obesity and diabetes. Arginine increases the amount of nitric oxide in the blood, a substance that relieves pressure on blood vessels, treats erectile dysfunction, and perhaps prevents erection problems. While there are many psychological and physical problems that can cause impotence, nitric oxide is helpful for those who need to increase blood flow. In addition, it helps in the treatment of angina, high blood pressure and other cardiovascular diseases. Most importantly, it does not have any drug side effects.